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How accurate is the AFP prenatal test in predicting Down's syndrome?
Posted: Mar 4, 2010
My niece is pregnant with her first child. She is young, 19 years old, so she is not considered high risk. However, in her prenatal screening, she had what her doctor called "a slightly abnormal" AFP test. Everyone was pretty upset and I did a little research and found conflicting information. Some say the test should stop being performed because it is inaccurate.
My niece has decided to forego having an amniocentesis because she says it will not change her mind. She is having her baby. So basically we are all praying and hoping for the best. But I'm just wondering how accurate some of the prenatal screening tests are.
19 years ago when my sister was pregnant with my niece, one of my sisters prenatal tests came back positive for syphilis. It was a false positive, but my sister freaked out, accused her husband of cheating on her, and then had a follow up test that said she did not have syphilis. So it makes me wonder what is the point of some of these tests? All they really do is completely scare an already nearly hysterical hormonal woman. When I was pregnant I was paranoid about everything!
So what's the consensus?
;
AFP - mt
[ In Reply To ..]has a high false-positive rate. I was pg with twins and chose not to have this test performed and also refused amnio (I was age 30). I didn't need any extra stress! I'm so glad I left everything in God's hands.
When my daughter was pregnant at 19 her OB, of course, gave the (sm) - anon
[ In Reply To ..]spill about having the test done, as he had to, but went on to say that he personally would not suggest it if there was no family history, on either side of Down's, because there is such a high false-positive result.
Good luck with your niece!!!
With my third child, at age 38, I had the AFP.....sm - Cyndiee
[ In Reply To ..]as I had had the test for my first two, came out normal, my children were healthy as heck, so I figured why not continue the test. Well, it opened up a nightmare; my husband was out of work, I was not feeling well, had two very young children at home, and my OB called to say that the AFP figures were low, meaning a Down's syndrome child probably. He advised, to be sure, that I have an amniocentesis, because the AFT had about a 30% false-positive, and so I had the amnio right before Christmas, I had a horrible flu, it was painful, and I had cramps and bleeding for a couple of days, but I had to know. But I had already made up my mind that there was no way I would abort, I know Downs chldren in my town and they are beautiful and loving, and I trust in God. Well, on Chistmas Eve, my darling OB called and said "Got a Christmas present for you; we studied every chromosome of your baby on the amnio, and he is PERFECT. I was never so relieved or so very happy at Christmas. And in April of that year, I had a big bouncing baby boy, absolutely beautiful. But the stress, tears, waiting, is just horrible for a pregnant mother. And so I am ambivalent, they should tell all mothers how possibly inaccurate this test is. I pray it all turns out well!!!!
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